Melanotan 2

Melanotan II is a synthetic analog of the naturally occurring melanocortin peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that in usage has been shown to have melanogenesis (tanning) and aphrodisiac effects in clinical trial. Melanotan 2 is a cyclic lactam analog of α-MSH with the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2.

Legal Melanotan II Peptide has never been approved for use by any regulatory body outside of clinical trials. Melanotan II was first synthesized at the University of Arizona. They hypothesized that an effective way to reduce skin cancer rates would be to induce the body's natural pigmentary system to produce a protective tan prior to UV exposure. The naturally occurring hormone α-MSH causes melanogenesis, a process by which the skin's pigment cells (melanocytes) produce the skin's pigment (melanin). They tested to see if administering this endogenous hormone to the body directly could be an effective method to cause sunless tanning. What they found was that while it appeared to work, natural α-MSH had too short a half life in the body to be practical as a therapeutic peptide. So they decided to find a more potent and stable alternative, one that would be more practical.

After synthesizing and screening hundreds of molecules, the researchers found a peptide, Melanotan 1, that was approximately 1,000 times more potent than natural α-MSH. Scientists hoped Melanotan 2 peptides combat melanoma by stimulating the natural pigmentary mechanism to create a tan without first needing exposure to harmful levels of UV radiation. This in turn, they hypothesized, could reduce the potential for skin damage that can eventually lead to skin cancer.

Tanning analog of alpha-melanocyte stimulating hormone (α-MSH) was developed to improve melanin density

Melanotan tanning peptide alters melanin ratio at at the cellular level

Melanotan 2 (MT-II) is a melanotropin peptide analog of alpha-melanocyte stimulating hormone (a-MSH)

MT-II comes in the form of a freeze dried (lyophilized) peptide in a sterile multi-use vial

MT-II has a protective ring-like amino acid structure as compared to a linear peptide analog Melanotan 1

Reconstitute Melanotan II from freeze dried powder with bacteriostatic water (sterile water)

Melanotan 2 is a durable peptide that remains potent and preserved for months

After receiving Melanotan peptides it is recommended to store in a refrigerator